Biological System
Metabolic Dysfunction
When energy production breaks down, everything downstream suffers.
What it is
Metabolic dysfunction is the impaired ability of the body to convert food into stable cellular energy. It precedes most modern chronic disease.
Insulin resistance and glucose volatility erode mitochondrial output and downstream hormonal signaling.
Visceral adiposity drives chronic inflammation, which further blunts insulin sensitivity in a feedback loop.
Signs of dysfunction
- Mid-afternoon energy crash
- Brain fog after meals
- Increasing waist circumference
- Cravings for carbohydrate or sugar
- Fasting glucose creeping above 95 mg/dL
Levers
What moves the system.
Stabilize glucose
Walk after meals, prioritize protein, remove liquid calories.
See Fat Loss protocol →Zone 2 base
150 minutes of low-intensity aerobic work weekly to grow mitochondrial density.
See Longevity protocol →Recommended stack
Tools for this system.
References
- · Cell Metabolism, 2018 — Time-restricted eating in humans.
- · Diabetes Care, 2022 — Postprandial walking and glycemic control.